The Maintenance Schedule
Screening and check-ups by age, from the heel-prick test to your eighties. Reproduced from The Humanual, Volume 1: The Hardware, as printed. Free to read, print and photocopy.
You would not drive a vehicle for decades without periodic inspections. You are driving a far more complex machine with no option to trade it in. This appendix is the service schedule.
The purpose of preventive screening is to find problems early, when they are small, treatable, and far less expensive — in every sense — than the alternative. Specific timing varies by country and healthcare system. These are the principles and approximate intervals. Consult your local guidelines for the precise schedule. If a screening listed under an earlier stage also applies to yours, it still applies. The schedule is cumulative.
At Birth
What’s happening: the hardware has just come out of the box. It is, to put it mildly, unfinished. The immune system is naive, the neurological wiring is incomplete, the bones are partially cartilage, and the entire organism is dependent on another human for survival in a way that will not fully resolve for at least a decade and a half. Despite this, an extraordinary amount of screening happens in the first days of life, because several serious conditions are treatable only if caught before symptoms appear.
Newborn screening (heel prick / blood spot test): within the first 24 to 48 hours, a few drops of blood are taken from the baby’s heel and tested for a panel of congenital conditions. The exact number varies by country, but most programes screen for 30 or more conditions, including phenylketonuria (PKU), congenital hypothyroidism, sickle cell disease, cystic fibrosis, and a range of metabolic disorders. Many of these conditions are rare, but the ones that are caught and treated early can be the difference between a normal life and severe disability or death. The test is quick, it is routine, and there is no good reason to decline it.
Hearing screening: usually performed before the baby leaves hospital. Congenital hearing loss affects roughly 1 to 3 in every 1,000 newborns, and early detection is critical for language development.
Critical congenital heart disease (CCHD) screening: a simple, painless pulse oximetry test, typically performed in the first 24 to 48 hours. It measures oxygen levels and can detect heart defects that are not apparent on physical examination.
First vaccinations: in most countries, the hepatitis B vaccine is given at birth or within the first days of life. This is the beginning of the immunization schedule, not an optional extra.
Vitamin K: administered at birth (by injection or oral drops, depending on the country) to prevent a rare but potentially fatal bleeding disorder. The baby’s blood does not clot efficiently at birth; vitamin K fixes this. It has been standard practice for decades.
Ages 1 to 4
What’s happening: the fastest period of physical and neurological development outside the womb. The brain is forming approximately 1 million new neural connections per second during the first few years. Language, motor skills, social behavior, and attachment patterns are all being laid down. The immune system is being educated through both exposure and vaccination.
Well-child visits: frequent. In the first year alone, most guidelines recommend visits at 1 month, 2 months, 4 months, 6 months, 9 months, and 12 months. These are not just weigh-ins. Each visit includes developmental milestone checks, growth tracking (height, weight, head circumference), and age-appropriate screenings. In the second and third year, visits continue at 15 months, 18 months, 24 months, 30 months, and then annually. If this seems like a lot of doctor visits, consider that you are monitoring the most complex construction project in nature.
Immunizations: the bulk of the childhood vaccination schedule occurs between 2 months and 4 years. The core vaccines protect against diseases that, within living memory, were killing and permanently disabling children in large numbers: diphtheria, tetanus, pertussis (whooping cough), polio, measles, mumps, rubella, Haemophilus influenzae type b (Hib), pneumococcal disease, rotavirus, hepatitis B, and varicella (chickenpox). The specific schedule varies by country, but the underlying principle does not: these vaccines work, and the diseases they prevent are serious.
Developmental screening: formal validated screening (such as the Ages and Stages Questionnaire) is recommended at 9, 18, and 30 months. Autism spectrum screening is recommended at 18 and 24 months. Early identification leads to early intervention, which produces measurably better outcomes.
Vision: instrument-based screening may begin as early as 12 months. By ages 3 to 5, a visual acuity test should be performed. Conditions like amblyopia (lazy eye) are correctable in young children and increasingly difficult to treat with age.
Dental: the first dental visit is recommended by age 1 or when the first tooth appears. Fluoride varnish application is recommended from 6 months through age 5. Dental caries (cavities) are the most common chronic disease in young children, and they are preventable.
Lead screening: recommended at ages 1 and 2 in many countries, particularly in older housing. Lead exposure at low levels causes irreversible cognitive damage.
Ages 5 to 11
What’s happening: slower, steadier growth. The brain continues to develop, particularly the regions governing impulse control, social reasoning, and abstract thinking. School introduces new cognitive demands and, often, the first sustained peer comparisons. This is when many learning differences and attentional issues become apparent.
Annual well-child visits: continue. These include growth monitoring, blood pressure screening (recommended annually from age 3), and behavioral/social/emotional assessment.
Vision: visual acuity screening at ages 4 and 5, then as indicated.
Cholesterol: a one-time universal lipid screening is recommended between ages 9 and 11. This catches familial hypercholesterolaemia, a genetic condition that is far more common than most people realize and that benefits enormously from early management.
Immunization boosters: typically between ages 4 and 6, boosters are given for DTaP, polio, MMR, and varicella.
Dental: every six months. Orthodontic evaluation typically occurs in the early teens.
HPV vaccine: can begin as early as age 9. The evidence increasingly supports earlier initiation (age 9 to 12) for optimal immune response and higher completion rates. When given before age 15, only two doses are needed rather than three. This vaccine prevents cancer. That sentence bears repeating until it no longer needs to.
Ages 12 to 19
What’s happening: puberty. The endocrine system reboots, triggering growth spurts, sexual development, body composition changes, and a neurological remodeling project that will not be complete until the mid-twenties. The prefrontal cortex (the bit responsible for impulse control, long-term planning, and evaluating consequences) is the last region to finish developing, which explains a great deal about the decision-making of teenagers and should probably be printed on a card and handed to every parent who has ever said “what were you thinking?”
Immunizations: the adolescent platform, typically at 11 to 12, includes Tdap (tetanus, diphtheria, pertussis booster), meningococcal conjugate vaccine, and the HPV vaccine series if not already started. A meningococcal booster is typically given at 16. Annual flu vaccine continues.
Depression screening: recommended annually from age 11 onward. This is the critical window. Half of all lifetime mental health conditions emerge by age 14. Three-quarters by age 24. Depression, anxiety, eating disorders, self-harm, and the early signs of more complex conditions frequently surface during adolescence. The single most important thing an adult can do is take a teenager’s distress seriously and not dismiss it as “just a phase.” It might be. It also might not, and the cost of assuming wrong in one direction is infinitely higher than the other.
Substance use screening: recommended for older adolescents. The validated CRAFFT questionnaire (Car, Relax, Alone, Forget, Friends, Trouble) is designed for this age group.
Blood pressure: annually from age 3, continuing through adolescence.
Scoliosis: screening typically occurs in early adolescence, checking for spinal curvature that may require monitoring or intervention during growth.
Sexual health: STI screening for sexually active adolescents. Accurate information from a healthcare provider or evidence-based source — not from peers or the internet — is protective. Shame is not.
HIV screening: recommended at least once between ages 15 and 21.
Skin: sun protection habits established now prevent skin cancer decades later. The sunburns you get before age 20 disproportionately increase lifetime melanoma risk. Sunscreen is not optional.
Sleep: teenagers genuinely need more sleep than adults (8 to 10 hours), and their circadian rhythm shifts later — the biological drive to stay up late and sleep in is not laziness, it is physiology. School start times in much of the world are at war with adolescent neuroscience, and the neuroscience is correct.
Dental: every six months. Still.
Your 20s
What’s happening: the brain’s prefrontal cortex finishes developing around age 25. You are establishing the baseline patterns that will follow you for decades. Building them now is vastly easier than rebuilding them later.
Blood pressure: every two years if normal. This is the one screening that applies at every age. High blood pressure produces no symptoms until it produces a stroke, heart attack, or kidney failure. The only way to know is to measure it. Home monitors are inexpensive and widely available.
Cholesterol: get a baseline lipid panel. This gives you and your doctor a reference point for the rest of your life.
Cervical screening: begins at age 25 for individuals with a cervix. Primary high-risk HPV testing every five years is now the preferred method. Self-collection of vaginal samples for HPV testing is approved in many healthcare systems — a fully valid option that does not require a clinical speculum exam. Where self-collection is not yet available, Pap smears remain effective. The key: get screened, by whichever method your system offers.
Skin: begin regular self-examination. Learn the ABCDE rule: Asymmetry, Border irregularity, Colour variation, Diameter over 6 mm (¼ in), Evolving. Know your moles. Professional checks if you have significant risk factors (fair skin, history of sunburns, family history of melanoma, many moles).
Dental: every six months. Dental problems do not resolve themselves; they compound. An ignored cavity becomes a root canal becomes an extraction becomes an implant, each stage more expensive and unpleasant than the last.
Eyes: as needed in your twenties, moving to every two years from your thirties.
Immunizations: tetanus/diphtheria booster every ten years. Annual flu vaccine. HPV vaccine if not previously vaccinated. Check your local schedule for anything else recommended at your age.
Sexual health: STI screening if sexually active, particularly with new or multiple partners. This is routine maintenance, not a moral judgment.
Your 30s
What’s happening: metabolism begins a gradual slowdown (not the cliff-edge people describe, but measurable). The problems that present at 45 are being quietly built now by how you sit, move, eat, and sleep.
Blood sugar: screening begins at 35, or earlier if you have risk factors (family history, obesity, history of gestational diabetes). Pre-diabetes is common, usually asymptomatic, and frequently reversible with lifestyle changes if caught. Type 2 diabetes is significantly less reversible.
Cholesterol: follow-up based on your baseline and risk factors. If your twenties panel was normal, every five years is typical.
Cervical screening: continues. HPV testing every five years (self-collected or clinician-collected).
Breast awareness: know what is normal for you. Mammography screening for high-risk individuals may begin now — discuss with your doctor if you have a strong family history or known genetic risk (e.g. BRCA mutations).
If planning pregnancy: preconception health matters for both partners. Folic acid supplementation, substance use review, health screening, understanding fertility timelines. Fertility declines with age in all bodies, more steeply after 35 in those with ovaries. This is a biological reality, not a judgment — and understanding it allows for informed planning.
Everything from your 20s continues: blood pressure every two years, dental every six months, skin self-checks, annual flu vaccine, tetanus booster on schedule.
Your 40s
What’s happening: this is where screening expands significantly. The conditions being screened for are largely asymptomatic in their early stages, which is precisely why screening matters.
Breast cancer: mammography begins at 40, biennial, through at least age 74. The evidence now firmly supports 40 as the starting age, not 50. Earlier recommendations hedged; current evidence has resolved this.
Colorectal cancer: screening begins at 45. Options vary by country: colonoscopy, faecal immunochemical testing (FIT), stool DNA tests, and others. The method matters less than the doing. Colorectal cancer is highly treatable when caught early, significantly less so when it is not. If you are over 45 and have not been screened, this is your prompt.
Eyes: every two years. Presbyopia (difficulty focusing on close objects) typically begins in the forties. This is not a disease; it is the lens losing elasticity with age. It happens to essentially everyone.
Everything from earlier stages continues: blood pressure, cholesterol, blood sugar, cervical screening, dental, skin, immunisations.
Your 50s and 60s
What’s happening: the body’s repair mechanisms slow. Muscle mass declines more noticeably (sarcopenia). Bone density decreases, particularly in postmenopausal women. The conditions that were being silently screened for in the previous decades become statistically more likely. This is also, paradoxically, when life satisfaction often begins rising again after its mid-forties dip — the research on this is remarkably consistent across cultures.
Prostate cancer (PSA): this is a conversation with your doctor, not a blanket recommendation. Typically discussed from age 50. The PSA test has a significant rate of false positives, and management of screen-detected cancers is not straightforward. This is one area where informed, individual decision-making genuinely applies.
Lung cancer: annual low-dose CT for adults aged 50–80 with a significant smoking history (roughly 20 pack-years — one pack per day for 20 years, or equivalent). If you qualify, this screening saves lives.
Shingles vaccine: recommended from age 50. Shingles is the reactivation of the chickenpox virus, which has been quietly living in your nerve cells since childhood, waiting. The vaccine significantly reduces the risk.
Bone density: DEXA scanning may be recommended, particularly for postmenopausal women and those with risk factors for osteoporosis.
Menopause and hormone therapy: if you are experiencing menopause, the question of whether hormone replacement therapy is appropriate is a conversation with your doctor, not the internet. The risk-benefit profile has been significantly reassessed in recent years and depends on your individual health history, the timing of initiation, and the severity of your symptoms. Current evidence is considerably more favourable than the headlines of twenty years ago suggested.
Testosterone: levels decline gradually with age in all bodies. If you are experiencing symptoms (persistent fatigue, reduced libido, mood changes), testing is straightforward and a conversation with your doctor is worthwhile. Treatment is a medical decision, not a lifestyle upgrade — and the booming online testosterone industry is selling to insecurities, not diagnoses.
Blood pressure: screening frequency increases to at least annually.
Everything from earlier stages continues. Mammography, colorectal screening, cervical screening (through age 65), dental, eyes, immunizations.
65 and Beyond
What’s happening: the machine requires more attentive maintenance, but “older” does not mean “failing.” A significant portion of what people attribute to ageing is accumulated lifestyle factors, and many of the interventions that matter most — movement, social connection, cognitive engagement — become more important, not less.
Eyes: annually. Glaucoma, macular degeneration, and diabetic retinopathy can all be caught by routine exams before they cause irreversible damage.
Hearing: hearing loss is gradual and frequently unrecognized by the person experiencing it. If people around you are commenting, get tested. Untreated hearing loss is associated with social isolation, cognitive decline, and depression.
Pneumococcal vaccine: recommended at 65 if not previously received.
RSV vaccine: a single dose recommended for adults over 75, or those 60–74 with elevated cardiopulmonary risk.
Cervical screening: generally stops around 65 if previous screenings have been normal.
Colorectal screening: typically continues through age 75. Beyond that, the decision is individual.
Falls prevention: this is not a screening but it belongs here. Falls are the leading cause of injury-related death in older adults. Strength training, balance exercises, home modifications (removing trip hazards, installing grab bars), and medication review (many medications affect balance) are concrete, effective interventions.
Everything else continues: blood pressure, cholesterol, blood sugar, dental, skin, mammography, lung cancer screening if applicable, flu vaccine annually, other immunizations per schedule.
A Note on Immunizations
Vaccines are not exclusively for children. The specific schedule varies between countries, and in some places the recommended schedule itself has become a source of political rather than scientific debate. When guidance from different bodies conflicts, the guiding principle is always the same: follow the epidemiological evidence, not the political posturing. The pathogens have not changed. Consult a qualified healthcare provider you trust.
A Note on Access
This schedule assumes you have access to healthcare. Many people do not. This is not a personal failing; it is a systemic one, and it is not equally distributed. Where community clinics, public health services, or subsidized care exist, use them. Your health is worth whatever navigation your local system requires.
Other pages, printable
New pages are added as they are finished, and the index is always the current list. The Toolkit indexThe five volumes

